background: pediatric patients on chemotherapy are vulnerable to invasive fungal infection especially candida spices. resistance to antifungal agents has increased in candida spp., especially in non-albicans species. this study aims to assess the susceptibility of candida spp. strains isolated from children with acute leukemia less than 18 years. materials and methods: this prospective cross-se...

background although medical oncologists can have an important role in controlling the cost of cancer treatment, there is little information about their attitudes toward the cost of cancer treatment and the impact of cost on their treatment recommendations, especially in low- and middle-income countries (lmics). in this study, we assessed the attitude of iranian medical oncologists toward some e...

introduction: allocation of the new (expensive) drugs for difficult refractory diseases and financial protection of the patients is an important challenge in the national health systems worldwide especially in developing countries.â  trastuzumab (herceptin) as one of the effective but expensive drugs, put major financial burden for the iranian patients and government. so the ministry of health ...

the application of chemotherapy in cancer treatment has been limited due to cause side effects such as toxicity against normal cells and drug resistance. in recent years, numerous studies have been focused on using natural products with chemotherapeutic drugs to enhance therapeutic efficiency and reduce cytotoxicity. on the other hand, encapsulation of drugs into nanoparticles (nps) can improve...

we aimed to develop a cost-effective and robust method to predict drug resistance in individualpatients. representative tissue fragments were obtained from tumors removed from femalepatients, aged 24-74 years old. the tumor tissue was taken by a histopathology’s or a surgeonunder sterile conditions. cells obtained by enzymatic dissociation from tumor after surgery, werecultured as a monolayer f...

pluronic based nano-particulate systems are innovative platforms for delivery of anti-cancer agents. these systems due to their pharmacological properties and suitable physicochemical characteristics are great opportunity for development cancer therapeutics. this mini-review tries to provide a more detailed overview on the currently available pluronic based drug delivery systems. in the section...

cancer patients are more susceptible to adverse drug-drug interactions (ddis) due to receiving multiple medications especially chemotherapy medications, hormonal agents and supportive care drugs. the aim of this study is to describe the prevalence of potential ddis and to identify risk factors for these potential interactions in hospitalized cancer patients in a developing country.a cross-secti...

The application of chemotherapy in cancer treatment has been limited due to cause side effects such as toxicity against normal cells and drug resistance. In recent years, numerous studies have been focused on using natural products with chemotherapeutic drugs to enhance therapeutic efficiency and reduce cytotoxicity. On the other hand, encapsulation of drugs into nanoparticles (NPs) can improve...